Bis-Tris Propane (sometimes called BTP) is a zwitterionic Good’s buffer used in biological and biochemical research. It has a broad buffering range that makes it versatile for experiments requiring stable pH control from near neutral to alkaline conditions.
- Wide buffering range: pH 6.3–9.5
- Two pKa values (~6.8 and ~9.0) contribute to broad range
- High water solubility
- Low biological interference
- Supports stable environments for enzymes and proteins
Bis-Tris Propane is commonly used in protein research, enzyme studies, electrophoresis, nucleic acid purification, and other applications where a broad pH buffering range is useful.