PIPES

PIPES buffer (Piperazine-N,N′-bis(2-ethanesulfonic acid)) is a reliable Good’s buffer for biochemistry and molecular biology applications requiring stable pH control. With a pKa of approximately 6.8, PIPES is effective within a pH range of 6.1 to 7.5, making it ideal for cell culture, enzyme assays, and protein purification. Its low metal ion binding and chemical stability ensure compatibility with gel electrophoresis, electron microscopy, and protein crystallization.

• Maintains pH stability for consistent experimental results
• Low interaction with metal ions supports sensitive biochemical assays
• Versatile applications in chromatography, isoelectric focusing, and microscopy

Widely used in biochemical research and structural biology, PIPES buffer provides the stability and reliability needed for precision-driven scientific experiments.