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CAPS

CAPS (3-cyclohexylamino-1-propanesulfonic acid) is a zwitterionic buffer used in biological and biochemical research to maintain stable pH in strongly alkaline systems. It is especially useful for high-pH applications where standard near-neutral buffers are not effective.

  • pKa (25 °C): ~10.4
  • Effective buffering range: pH 9.7–11.1
  • Highly soluble in water
  • Low UV absorbance
  • Minimal interaction with proteins and enzymes

CAPS is commonly used in protein research, high-pH enzyme assays, Western blot transfer buffers, and other applications requiring reliable buffering at alkaline pH.

CAPS

Showing 1–2 of 2 products

CAPS Buffer (0.5 M, pH 11.0)

CAPS Buffer (0.5 M, pH 11.0)

From: $101.00

CAPS Buffer (0.5 M, pH 10.0)

CAPS Buffer (0.5 M, pH 10.0)

From: $101.00

FAQs

Products & Formulation

CAPS buffers effectively in the alkaline range from about pH 9.7 to 11.1, with optimal buffering near pH 10.4.

Use CAPS when you need stable buffering in strongly alkaline conditions — for example, in high-pH enzyme assays, protein electrophoresis transfer systems, or other biochemical applications that require pH well above neutral.

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