Maximize recovery with optimized downstream bioprocessing buffers

Do you need to recover, concentrate, and purify recombinant proteins, monoclonal antibodies or other bioproducts? If so, you've likely experienced issues with yield, purity, and bioactivity. These issues are often associated with inappropriate or inconsistent buffer conditions during purification steps.

Let us help! We offer high-quality custom buffers specifically designed for downstream bioprocessing applications, helping you get back on track quickly and easily.

How we simplify the process

We offer high-performance buffers when you need them, so you can purify with confidence and establish a supply chain that meets your timelines. Our custom-formulated reagents reduce inconsistency during your downstream bioprocessing workflow. This saves you time and helps you obtain highly purified recombinant proteins, monoclonal antibodies (mAbs), non-viral vectors, and viral vectors run after run.

We take a collaborative approach to optimize salt concentration, pH, and other components necessary to isolate tagged-fusion proteins and other bioactive products with chromatography. Our track record of success and stringent quality assurance measures allow us to confidently fulfill your requirements and deliver downstream bioprocessing buffers and reagents tailored to your needs.

How you benefit when you partner with Boston BioProducts


Get time back with custom buffer manufacturing and ready-to-use buffers

Improve productivity and save time by letting our experts make your buffers. Boston BioProducts is committed to providing custom-formulated buffers by offering precise pH, salt conditions, and other unique additives. With quick turnaround times, you can rest assured that our experienced team will help you manufacture the buffers you need.

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Efficiently optimize protocols and buffer recipes

It's tough to juggle limited resources, deal with variability in starting materials, and navigate the complexity of the process. Tap into our expertise to streamline optimization. We provide technical consultations to help identify the correct pH and salt conditions for the best yield and purity of your recombinant proteins, mAbs, and vectors.

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Establish reliable chromatography and polishing runs

Use our buffers, to purify biomolecules that fuel the R&D of tomorrow's therapeutics. We make all buffers and solutions in-house so quality results are guaranteed. Our buffers are specifically designed for Protein A Chromatography, polishing steps, and more so you can build your research on a stable foundation.

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Simplify your supply chain

It is hard to find high-quality raw materials, deal with long lead times, ensure quality control, and manage unexpected disruptions. On top of that, addressing compatibility issues with different suppliers makes things even tougher! By manufacturing our buffers in-house, we offer readily-available customized solutions, fast turnaround times, and competitive pricing so you get the high-quality products you need without delay.

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Boston BioProducts can help

Featured Services & Resources


Custom Buffer Manufacturing

For a seamless process, trust Boston BioProducts to bring your desired formulation and specifications to life. Whether you need reproducibility, top-tier raw materials or efficient buffers, we guarantee high-caliber results.

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Quality Assurance

By using carefully vetted suppliers and fostering a culture of quality control, we create reliable products that will bolster your laboratory's capabilities.

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Our Facilities

To guarantee consistent quality, we manufacture all buffers within a 115,000+ ft2 certified facility to ISO standards. Our state-of-the-art machinery and validated documentation also produce fast reliable results for clients like you.

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Frequently Asked Questions

Downstream bioprocessing purifies, isolates, and concentrates a desired product, such as proteins, monoclonal antibodies, non-viral vectors, and viral vectors, from cell cultures and complex mixtures.

Downstream bioprocessing involves several steps, including clarification, capture, purification, concentration, and formulation.

Each step in downstream bioprocessing is carefully optimized and validated to ensure the quality, purity, and efficacy of the final product.

Downstream bioprocessing is challenging for several reasons. Protocol and buffer optimization is particularly time-consuming. Boston BioProducts offers custom buffer manufacturing for purifying recombinant proteins and monoclonal antibodies. Our experienced scientists can provide technical consultations to help optimize your downstream bioprocessing protocols.

Improving downstream bioprocessing starts with selecting the appropriate buffer conditions. Optimizing pH and salt gradients during purification steps is crucial to enhancing separation and maintaining bioactivity. Using appropriate lysing conditions may also improve yield. Boston BioProducts offers high-quality buffers at every step of your downstream bioprocessing protocols.

Downstream bioprocessing products include recombinant proteins, monoclonal antibodies, non-viral vectors, viral vectors, lipids, and other potentially useful isolated biological components.