Sodium cacodylate buffer is an aqueous organic compound producing inorganic trivalent arsenic when metabolized with an effective pH buffering capacity in the range of 5.1 to 7.4. It is particularly valued for its compatibility with fixatives and its ability to maintain stable pH conditions during specimen preparation.
Chemically stable under electron beam exposure, supporting artifact-free imaging
Does not react with common contrast agents, preserving staining integrity
Preserves fine cellular and subcellular detail for high-resolution imaging
Whether you're conducting transmission electron microscopy, scanning electron microscopy, or other ultrastructural studies, our sodium cacodylate buffer ensures reliable performance and high-quality results.
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Frequently Asked Questions
What is sodium cacodylate buffer used for?
Sodium cacodylate buffer is commonly used in electron microscopy applications, including transmission and scanning electron microscopy, due to its effective pH buffering capacity.
Why choose sodium cacodylate buffer over other buffers?
Sodium cacodylate buffer offers excellent pH stability, compatibility with various fixatives, and minimal interaction with cellular components, making it ideal for electron microscopy.
Why is sodium cacodylate buffer used in microscopy?
Sodium cacodylate buffer is widely used in electron microscopy because it maintains a stable pH during fixation, which is essential for preserving cellular ultrastructure. It is also highly compatible with fixatives like glutaraldehyde and osmium tetroxide, helping to reduce artifacts and improve image contrast.
