Our goal? Simple: be the clear choice. At Boston BioProducts, what sets us apart isn't just what we do, it's how we do it. In a competitive market, customers always have options: make it themselves, go with another vendor, or choose us. Our goal is to make that decision easy. We differentiate ourselves by offering more than just high-quality reagent...
Absorbance Testing Absorbance testing is a technique that measures the amount of light absorbed by a sample at a specific wavelength. Dissolved analytes such as molecules or ions have distinct arrangements of atoms connected by chemical bonds. When photons of light interact with these bonds, ground-state electrons can be promoted to an excited state at a higher energy level. The...
Sterility Testing Sterility Testing is a critical quality control procedure to ensure the absence of viable microorganisms in buffers, reagents, and media. Even minimal microbial growth can significantly alter the pH, ionic strength, and stability of a buffer, affecting its behavior and compromising experimental reproducibility or further manufacturing processes. The most widely used methodology for this testing is USP <71>...
Bioburden Testing Bioburden testing, is a quality control measurement standard used to assess microbial contamination present on various surfaces, equipment, or products. A common methodology for measuring this is USP <61> . This testing is used in industries where maintaining sterile environments and products is important. Bioburden enumeration is key in understanding the levels of microorganisms in each product during...
Microbial Growth Testing Microbiological contamination refers to the unintended introduction of microorganisms or microbes, such as bacteria, yeast, mold, fungi, and/or their by-products, into a given environment, solution, or product. History of Microbial Growth Testing The history of microbial growth testing traces back centuries, beginning with early observations of microorganisms and further developing into modern microbiological techniques. Today, microbial growth...
Endotoxin Testing Endotoxins, also known as lipopolysaccharides (LPS), are toxic substances found in the outer membrane of Gram-negative bacteria. These endotoxins are released into the environment when bacterial cells die or undergo lysis. History of Endotoxin Testing Endotoxin testing has evolved over the years, starting from pyrogen testing to more refined methods like gel clot, turbidimetric, or quantitative chromogenic Limulus...
Protease Testing A Protease Assay is a quality control measure employed to identify and quantify the presence of proteases in various biological buffers, reagents, and solutions. Proteases are found ubiquitously in organisms like plants, animals, and microbes and are responsible for degrading protein aggregates, managing genome translation, and adhering to cellular structural guidelines . Proteases are essential in ending the...
RNase Testing The RNase Assay, short for Ribonuclease Assay, is an analytical process in molecular biology. It involves the assessment of ribonuclease activity in biological samples and solutions. Ribonucleases (RNases) are enzymes that degrade ribonucleic acid (RNA) molecules that are naturally occurring and found across various organisms, particularly in bacteria and fungi. History of RNase Testing The history of the...
DNase Testing DNase, or Deoxyribonuclease, is an enzyme that catalyzes the hydrolytic cleavage of the phosphodiester backbone of DNA. It can digest single- and double-stranded DNA, chromatin, and DNA-RNA hybrids. DNases play a vital role in various cellular functions and are essential for research and biotechnological applications. Since these enzymes are ubiquitous, they can cause contamination if exposed to certain...
Refractive Index Testing Refractive Index is an optical characteristic of a substance, representing the number of dissolved particles in the substance. It is defined as the ratio of the speed of light in empty space to the speed of light in the substance, calculated using Snell's law: n₁ sin(θ₁) = n₂ sin(θ₂) Where: n₁ = Incident index n₂ = Refracted...
