Protease Testing A Protease Assay is a quality control measure employed to identify and quantify the presence of proteases in various biological buffers, reagents, and solutions. Proteases are found ubiquitously in organisms like plants, animals, and microbes and are responsible for degrading protein aggregates, managing genome translation, and adhering to cellular structural guidelines . Proteases are essential in ending the...
RNase Testing The RNase Assay, short for Ribonuclease Assay, is an analytical process in molecular biology. It involves the assessment of ribonuclease activity in biological samples and solutions. Ribonucleases (RNases) are enzymes that degrade ribonucleic acid (RNA) molecules that are naturally occurring and found across various organisms, particularly in bacteria and fungi. History of RNase Testing The history of the...
DNase Testing DNase, or Deoxyribonuclease, is an enzyme that catalyzes the hydrolytic cleavage of the phosphodiester backbone of DNA. It can digest single- and double-stranded DNA, chromatin, and DNA-RNA hybrids. DNases play a vital role in various cellular functions and are essential for research and biotechnological applications. Since these enzymes are ubiquitous, they can cause contamination if exposed to certain...
Refractive Index Testing Refractive Index is an optical characteristic of a substance, representing the number of dissolved particles in the substance. It is defined as the ratio of the speed of light in empty space to the speed of light in the substance, calculated using Snell's law: n₁ sin(θ₁) = n₂ sin(θ₂) Where: n₁ = Incident index n₂ = Refracted...
Density Testing Density measurement, otherwise known as specific gravity measurement, is an analytical technique that quantifies the mass per unit volume of a substance. Typically expressed in units such as g/mL or kg/L, this parameter assesses the physical characteristics of all materials and is unique to each material composition. Density measurement is one of the many quality control tests at...
Osmolality Testing Osmolality is a test used to measure the concentration of solute particles dissolved in a solution, expressed as Osmoles (Osm) or milliOsmoles (mOsm) per kilogram of solvent (Osm or mOsm/kg H2O). A common methodology for measuring this is USP <785>. It is a useful test in various scientific and medical applications, including assessing the solute content in solutions...
Conductivity Testing Conductivity Testing is the assessment standards of a solution's ability to conduct electricity through the movement of charged ions. A common methodology is USP <644>. Conductivity is usually measured as milli-Siemens/cm (mS/cm) or micro-Siemens/cm (μS/cm). History of Conductivity Testing Conductivity measurement can be traced back to the 19th century when scientists began to explore the electrical properties of...
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Reagent Quality Control Testing at Boston BioProducts Explore our growing testing services to learn more about how you can create a reagent that can work for you. Contact Us Our Offerings At Boston BioProducts, our custom offerings are not just limited to our comprehensive list of reagent formulation possibilities, but also our quality control testing on finished product. Our Quality...
pH Testing pH measurement is an analytical technique that quantifies the acidity or alkalinity of aqueous solutions. It provides insight into the concentration of hydrogen ions (H+) in a solution and is a crucial parameter in various scientific disciplines, especially in the fields of chemistry and biology. A common methodology for measuring this is USP <791>. The pH scale ranges...
